means,

The breath of life in ma. The intelligent, immaterial, and immortal part of human beings.
Also, (superhumanly) an angel or demon.
Also, (divinely) God; Christ's Spirit; the Holy Spirit.

Having therefore these promises, dearly beloved, let us cleanse ourselves from all filthiness of the flesh and spirit, perfecting holiness in the fear of God.
2 Corinthians 7:1